Boot issues with Windows 10 PE

Hi

I have created a working PE using WAIK under Windows 10

If I boot the ISO file in VirtualBox it boots really quickly and works fine

If I burn the ISO to CD/DVD and boot it on a real machine I get the blue logo, but it then sits for absolute ages before the spinning circle appears and it starts to boot - it does eventually go in, but can take several minutes

If I create USB using (MakeWinPEMedia /UFD D:\PE_TEMP G:) then it creates fine, but when trying to boot I get blue screen error with "winload.efi error 0xc0000225"

Any thoughts please